DMB performed on the SanDisk Main Stage.
LeRoi Moore did not play at this show due to injury.
Lineup:
Dave Matthews Band, Tom Petty and the Heartbreakers,
John Mayer, The Black Crowes,
O.A.R.,
Michael Franti and Spearhead, Rodrigo y Gabriela, Steve Winwood, Spoon, Flogging Molly, Colbie Caillat, Onerepublic,
The Roots,
moe., Leftover Salmon, Citizen Cope, and more
Released as Live at Mile High Music Festival on December 16, 2008.
Rarity  | Rank | Tour | So Far |
| 48 of 48 | 2.036 | 2.030 |
| 4 of 5 | 1.896 | 2.236 |
| 7 of 7 | 3.923 | 3.000 |
| 7 of 7 | 2.833 | 3.000 |
| 22 of 25 | 4.500 | 3.522 |